Celtic have been drawn to play giant-killers Falkirk in the semi-finals of the Scottish Communities League Cup.
The other fixture has thrown up an Ayrshire derby, with Kilmarnock meeting Ayr United for a place in the final.
The ties will be played on 28 and 29 January, with Hampden Park the likely venue for both games.
First Division Falkirk have beaten cup holders Rangers and Dundee United en route to the last four of this season's tournament.
Ayr United have also taken Scottish Premier League scalps in the competition, upsetting Inverness, Hearts and St Mirren.
"I'm reasonably pleased, quite happy, it's a game everyone in Ayrshire will look forward to," said Ayr manager Brian Reid.
"The build-up will start right away and it should be a great game. A semi-final certainly adds an intensity to it."
The Ayrshire rivals will hold talks with the Scottish Football League over the choice of venue but Reid is leaning towards a day at the national stadium.
"We don't know how many will come or whether we will want to play at a half-full Hampden," added Reid.
"There was discussion of Tynecastle and I think we would certainly fill it but it's just whether the supporters would want to travel through there.
"I don't think there's a facility on the west coast that is sufficient.
"I would be surprised if we didn't get more than 20,000. We went to Rugby Park and we filled the whole away end and that was midweek.
"A semi-final on a weekend, you will get a lot of people from Ayr who maybe don't have a big interest normally and you'll have people from abroad that will come.
"People don't maybe realise what the Ayrshire derby means to a lot of people."
Celtic are the only side in the last four to have won the trophy before, with the last of their 14 triumphs coming in 2009.
Kilmarnock have been beaten finalists on five occasions, while Ayr United and Falkirk have both been to one final and lost.
Ayr United and Kilmarnock last met on Scottish Cup duty in 2009, with the SPL side prevailing after a 3-1 replay win at Rugby Park.
Scottish Communities League Cup semi-final draw:
Falkirk v Celtic
Ayr United v Kilmarnock