Liverpool goalkeeper Pepe Reina says playing at Wembley on Saturday evening will be particularly "special" for the Premier League's Spanish contingent.
Reina hopes for a place in Spain's team alongside former team-mate Fernando Torres, another Chelsea man Juan Mata and Manchester City's David Silva.
Spain also have four Premier League old boys in Cesc Fabregas, Gerard Pique, Xabi Alonso and Alvaro Arbeloa.
"For the people that play in England it is a special game," said Reina.
"Nowadays, there are no friendlies any more. Any time you go with your national team you want to win."
Liverpool favourite Reina has skippered the Reds in their last two matches following the loss to injury of Anfield linchpins Steven Gerrard and Jamie Carragher.
But, not only is he not even number one for his country, ranked behind Real Madrid's Iker Casillas, he has a battle simply to sit on the bench, with Barcelona's Victor Valdes.
Yet the 29-year-old, now in his seventh season at Anfield after moving from Villarreal in 2005 to replace Champions League hero Jerzy Dudek, is happy just to be part of the world champions' squad.
"In the national team, we are 23 very important players for our clubs but only 11 can start," 22-times capped Reina told BBC Radio Merseyside.
"We have to take that role when it comes along.
"Even when you are not playing, you are lucky enough to be there.
"In my particular case it has been an absolute pleasure to be involved and be champions of Europe and the world."