Arsenal have moved their Premier League game with Wolves back a day to 1500 GMT on 27 December because of industrial action on the London Underground.
The Tube network is set to be disrupted on Boxing Day, after attempts to halt the strike failed in the High Court.
An Arsenal statement read: "Paramount concern was always the duty of care towards supporters, and everyone who was planning to attend on Boxing Day."
Chelsea have confirmed their Boxing Day match with Fulham will still go ahead.
Aslef's 2,200 members agreed to strike over pay issues on Boxing Day, 16 January, 3 and 13 February.
London mayor Boris Johnson had hoped to avert the Boxing Day walkout but his challenge was dismissed by the judge.
In addition to the industrial action on the Underground on Boxing Day, one of the busiest shopping days of the year in London, no overground trains are due to stop in the capital.
Arsenal also stressed that parking restrictions close to the ground would have still applied.
"This would have caused severe disruption, or at worst, inability for supporters or matchday employees and workers to get to Emirates Stadium," the statement explained.
"We apologise for the inconvenience this may have caused supporters, but we feel that the right decision has been made based on a duty of care."
The club have confirmed that all tickets purchased for the match will still be valid for 27 December.
Wolves have said that any fans, who bought tickets but are unable to attend the rearranged fixture, are entitled to a full refund if they contact the ticket office before 1200 GMT on Saturday.
Chelsea have advised supporters to monitor transport websites and local radio stations, and allow plenty of time for their journeys to the west London derby with Fulham, which kicks off at 1300 GMT.