Rangers striker Nikica Jelavic will miss the SPL encounter at home to Hibernian through illness.
The 26-year-old, who has been linked with a £7m move to West Ham, is suffering from a sickness bug.
"I believe there was a bid from West Ham on Wednesday that was rejected," said manager Ally McCoist.
"He has a bug, a bit of sickness. The doctor went to see him on Wednesday and he wasn't well, and went to see him again this morning."
Jelavic has been linked with a move during the January transfer window, but West Ham's offer fell short of the club's valuation.
The striker's absence does little to ease McCoist's selection headache, with Kyle Lafferty and Steven Naismith both sidelined through injury.
David Healy is expected to lead the line against Hibs at Ibrox on Saturday.
"I believe the family has had it (the bug) as well and one or two of our younger players went down with it," the Rangers boss added.
"But I can absolutely assure you that the doctor has been to see him and he is not well enough to play and that's a fact."
Jelavic, who has scored 30 goals for Rangers, made the switch to Glasgow from Rapid Vienna in 2010 and helped deliver the title under Walter Smith last season.