Linfield and Derry City will clash at Windsor Park in the pick of Monday night's Setanta Sports Cup second round, first leg matches.
Derry, who started their Premier Division campaign with a 1-0 win over Bohemians, will be without striker Rory Patterson, who joined from the Blues.
Peter Thompson will hope to continue a run of scoring in his last five games.
Sligo Rovers' new boss Ian Baraclough will come up against Glentoran, who recently installed Eddie Patterson.
Ex-Crusaders player Aaron Callaghan will manage Bohemians against his former club at Seaview.
Defenders Colin Coates and Paul Leeman return for the Crues after missing the Irish Cup win over Coleraine.
Cliftonville manager Tommy Breslin is hopeful of having some of his injured players back for the away trip to cup holders Shamrock Rovers.
Setanta Sports Cup second round, first leg - Monday 5 March
Linfield v Derry City (1930 GMT)
Sligo Rovers v Glentoran (1945)
Shamrock Rovers v Cliftonville (1945)
Crusaders v Bohemians (1945)