Crusaders will start their defence of the League Cup with a second-round clash against Glebe Rangers or Larne at Seaview on 27 August.
Linfield face Ards or Annagh United in their opener while Glentoran will take on the PSNI or Chimney Corner.
Coleraine meet Ballymoney United, Portadown play Dundela and Cliftonville are home to Moyola Park or Tobermore.
There are 10 first-round games before Premiership clubs enter the competition in the second round.
Premiership newboys Ballinamallard start against Newtownbreda or Warrenpoint Town while Glenavon await the winners of the first-round game between Sport & Leisure Swifts and Wakehurst.
The third round round will be played on 9 October, followed by the quarter-finals on 5 November, semi-finals on 11 December and the final on 26 January, 2013.
Crusaders won the trophy last season thanks to a 1-0 victory over Coleraine in the decider.
Midfielder Chris Morrow scored the only in the Ballymena Showgrounds game in January.
Irn-Bru League Cup fixtures
First round - 14 August
Ards v Annagh Utd
Banbridge Town v Queen's University
Moyola Park v Tobermore Utd
Sport & Leisure Swifts v Wakehurst
Loughgall v Lurgan Celtic
Portstewart v H&W Welders
PSNI v Chimney Corner
Knockbreda v Warrenpoint
Dergview v Ballyclare Comrades
Glebe Rangers v Larne
Second round - 27 August
Ards/Annagh Utd v Linfield
Crusaders v Glebe Rangers/Larne
Killymoon Rangers v Carrick Rangers
Glentoran v PSNI/Chimney Corner
Dergview/Ballyclare Comrades v Newry City
Ballymena Utd v Loughgall/Lurgan Celtic
Cliftonville v Moyola Park/Tobermore Utd
Portstewart/H&W Welders v Donegal Celtic
Newtownbreda/Warrenpoint Town v Ballinamallard Utd
Bangor v Armagh City
Dundela v Portadown
Banbridge Town/Queen's University v Institute
Limavady Utd v Lisburn Distillery
Sport & Leisure Swifts/Wakehurst v Glenavon
Ballymoney Utd v Coleraine
Dungannon Swifts v Coagh Utd