MK Dons midfield pair Luke Chadwick and Daniel Powell will have injuries assessed before Tuesday's game.
Charlie MacDonald and Dean Bowditch have recovered from illness and injury respectively and Angelo Balanta returns after being ineligible for the FA Cup.
Leyton Orient boss Russell Slade has no new injury worries after their FA Cup tie at Gloucester City was postponed.
Keeper Jamie Jones is pushing for a return but Kevin Lisbie and Scott Cuthbert are doubts.
VIEWS FROM THE TRAINING GROUND
MK Dons manager Karl Robinson told BBC Three Counties Radio:
"They've got some gifted players who can win a football match. They went to Swindon and won 1-0. That's not an easy thing to do.
"They'll come here as the underdogs on Wednesday, but Russell Slade will be really looking forward to the test of playing against us.
"This will be another tough game."