Annan boosted their play-off hopes and heaped pressure on bottom-placed Stirling Albion with a big win at Galabank.
Goals from Scott Chaplain, Kieran McGachie, Michael Daly and a brace from defender Alistair Love secured the victory against nine-man Binos, who saw goalkeeper Samuel Filler and midfielder Gary Thom dismissed.
After Filler was shown red for serious foul play in the 20th minute, Love put the home team ahead 10 minutes later with a shot from close range before Chaplain netted his fourth league goal of the season.
Things got even worse for the visitors when Thom was sent off for serious foul play on the stroke of half-time.
Stirling attempted to rally with Graham Weir reducing the deficit on the hour mark. But minutes later McGachie slipped a right-footed shot in for the hosts.
Stephen Day then curled in a left-footed consolation from 12 yards for Stirling but Daly and Love sealed the win with two late strikes.
Annan Athletic: Mitchell, Blake, McGowan, Peter Watson, McKechnie, Steele, Love, Jardine (Thorburn 69), Chaplain (Sloan 62), Ramage (Daly 62), McGachie. Subs Not Used: Summersgill, Donley.
Booked: Jardine. Goals: Love 30, Chaplain 37, McGachie 67, Daly 85, Love 89.
Stirling Albion: Filler, McClune, McCulloch, Allison, McCunnie (Peat 23), Day, McSorley, Thom, Ferry, Graham Weir (Flood 76),White. Subs Not Used: Scott Davidson, Scott Davidson, Brass, Clarke.
Sent Off: Filler (21), Thom (45). Booked: Allison, Graham Weir, McCulloch.
Goals: Graham Weir 60, Day 73.
Ref: Gavin Ross