First Division leaders Partick Thistle stumbled to a surprise defeat at New Douglas Park, with Hamilton registering their first home win of the season.
Goalkeeper Graeme Smith had a Jags debut to forget when he fumbled Alister Crawford's corner into his own net.
Earlier, Accies' Steven May had blazed over from inside the area and Martin Canning's header was cleared.
Thistle improved after the interval but their hopes evaporated when Paul Paton was sent off for a bringing down May.
Hamilton: Cuthbert, Gordon, Canning, Page, McGlinchey (Ryan 72), Devlin, Longridge (Gillespie 70), Crawford, Routledge, Finnie (Fraser 79), May. Subs Not Used: Christie, Keatings.
Booked: Routledge, Ryan, Cuthbert. Goals: Smith 41 og.
Partick Thistle: Smith, Stephen O'Donnell, Muirhead, Archibald, Sinclair, Paton, Balatoni, Forbes, Lawless (McGuigan 67), Doolan, Erskine. Subs Not Used: Scully, Elliot, Bannigan, Murray.
Sent Off: Paton (75).
Ref: Stephen Finnie