Nuneaton climbed out of the Blue Square Bet Premier relegation zone after claiming a vital three points against fellow strugglers Gateshead.
Wesley York gave Boro the lead after 11 minutes when he poked in following good work by Aaron Phillips.
The hosts came close to levelling when Liam Hatch's close-range effort was superbly saved by keeper Lee Burge.
But the visitors doubled their advantage when Andy Brown turned home Simon Forsdick's delivery.
The Tynesiders had no reply and now lie just a point above the relegation zone with three games to play, one point below Nuneaton, who move up into 16th.