This year sees the Football League mark its 125th anniversary, and one of the founder members, Notts County, get the season up and running on Friday when they travel to take on Sheffield United in League One.
There is live radio commentary of that match on BBC Radio Nottingham and BBC Radio Sheffield, and there will be a match report on all BBC Sport Interactive platforms.
The season then starts in earnest on Saturday and there will be live text commentary on website, mobile and tablet, bringing you all the key incidents, goals and reaction from across the three divisions.
The day's action begins in the Championship, where north west rivals Burnley and Bolton clash in a lunchtime kick-off.
You can hear full live commentary of that game from 12:15 BST on Saturday on BBC Radio 5 live, with the station staying with the Championship action until 17:00 BST.
You can also follow the results as they come in on Final Score, which is live on BBC One, BBC One HD and BBC Sport Interactive from 16:25 BST.
In the 15:00 BST kick-offs, Harry Redknapp's relegated QPR welcome Sheffield Wednesday while Wigan head to Barnsley and the third demoted side Reading host Ipswich.
Newly promoted Yeovil are at Millwall and Leeds host Brighton.
In League One, the game of the day sees Preston welcome relegated Wolves, while in League Two Newport make their league return at home to Accrington and Portsmouth take on Oxford.
For a round-up of the day's goals, tune in to the Football League show on BBC One, BBC One HD or BBC Sport Interactive at 23:35 BST.
On Sunday, Derby play Blackburn in the only game of the afternoon. There will be a match report on BBC Sport and there is live radio commentary on BBC Radio 5 live.
As well as live text commentary, BBC Sport Interactive is the place to head to for live scores, fixtures, match reports and results throughout the season.