Match ends, Tranmere Rovers 0, Leyton Orient 4.
Kevin Lisbie scored twice as Leyton Orient maintained their lead at the top of League One with a win at Tranmere.
The 35-year-old striker converted Lloyd James's cross and then turned in Dean Cox's shot to make it 2-0.
Lisbie was then involved in a clash that led to home defender Ian Goodison being sent off for violent conduct.
David Mooney failed to score the resulting penalty, but Cox and Shaun Batt both fired in from the edge of the box to complete Tranmere's misery.
Orient's closest challengers, Peterborough, also won on Saturday to stay within a point of the leaders.
The Londoners remain the only unbeaten side in the division, a record they kept thanks to Lisbie's brace which takes his goal tally this term to 11 from 14 appearances.
Tranmere have taken just two points from six home games this season, conceding 17 goals in the process, and have not won a league fixture at Prenton Park since 24 March.
They almost levelled towards the end of the first half, but visiting goalkeeper Jamie Jones pushed Ash Taylor's header onto a post, while Orient's Mathieu Baudry was also denied by the woodwork with the score at 1-0.
VIEW FROM THE DRESSING ROOM
Tranmere manager Ronnie Moore told BBC Radio Merseyside:
"The way we collapsed was embarrassing. There was nothing in the game in the first half. We were a bit unlucky to be 2-0 down, and then 'Goody' does something stupid that's let everybody down.
"It was a bad tackle and they've had a little get-together, but you can't do what he's done.
"It's been on the cards for a couple of weeks because he got away with it at Bradford, where I thought he shouldn't have been sent off, but he was involved.
"Referees aren't stupid and they're going to look for it. You can't stand up and slap someone in the face."
Leyton Orient manager Russell Slade told BBC London 94.9:
"Particularly in the second half, I felt we went up into our top gear and we were more like ourselves, and the pleasing thing was we continued to create chances all afternoon.
"Kevin Lisbie was excellent today and he could have had more. He didn't take the penalty for his hat-trick but it doesn't matter who scores, as long as we keep creating and scoring.
"It was pleasing to win away from home, but to also keep a clean sheet was a great effort. We have not had a great record here over the years so it was a great result."
- 5GoodisonBooked at 64mins
- 6HateleySubstituted forSodjeat 62'minutes
- 9LoweBooked at 78mins
- 23RidehalghBooked at 45minsSubstituted forBell-Baggieat 62'minutes
- 6BaudryBooked at 56mins
- 11OdubajoSubstituted forLasimantat 81'minutes
- 10MooneySubstituted forStockleyat 85'minutes
- 9LisbieSubstituted forBattat 72'minutes
- Richard Clark
- Shots on Target
Second Half ends, Tranmere Rovers 0, Leyton Orient 4.
Abdulai Bell-Baggie (Tranmere Rovers) wins a free kick in the attacking half.
Foul by Romain Vincelot (Leyton Orient).
Abdulai Bell-Baggie (Tranmere Rovers) wins a free kick in the defensive half.
Foul by Shaun Batt (Leyton Orient).
Foul by Max Power (Tranmere Rovers).
Dean Cox (Leyton Orient) wins a free kick in the defensive half.
Substitution, Leyton Orient. Jayden Stockley replaces David Mooney.
Goal! Tranmere Rovers 0, Leyton Orient 4. Shaun Batt (Leyton Orient) left footed shot from the left side of the box to the bottom right corner. Assisted by Yohann Lasimant.
Corner, Tranmere Rovers. Conceded by Lloyd James.
Corner, Tranmere Rovers. Conceded by Mathieu Baudry.
Corner, Leyton Orient. Conceded by Jimmy McNulty.
Substitution, Leyton Orient. Yohann Lasimant replaces Moses Odubajo.
Attempt blocked. Moses Odubajo (Leyton Orient) right footed shot from outside the box is blocked.
Ryan Lowe (Tranmere Rovers) is shown the yellow card.
Goal! Tranmere Rovers 0, Leyton Orient 3. Dean Cox (Leyton Orient) right footed shot from the centre of the box to the bottom right corner. Assisted by Lloyd James.
Corner, Leyton Orient. Conceded by Ash Taylor.
Attempt blocked. Dean Cox (Leyton Orient) right footed shot from the centre of the box is blocked.
Foul by Jimmy McNulty (Tranmere Rovers).