Cardiff City have been drawn at home to holders Wigan Athletic in the FA Cup fifth round while Swansea will be away at Everton.
Swansea will be away to Everton, managed by ex-boss Roberto Martinez.
The Swans have never beaten Everton in 17 attempts.
The games will be played on the weekend of 15-16 February.
Full fifth round draw
Manchester City v Chelsea
Sheffield United or Fulham v Nottingham Forest or Preston North End
Arsenal v Liverpool
Brighton & Hove Albion v Hull City
Cardiff City v Wigan Athletic
Sheffield Wednesday v Charlton Athletic
Sunderland v Southampton
Everton v Swansea City