Napoli 1-0 Roma
Napoli earned a vital win in the Champions League qualification race as second-placed Roma lost further ground on Serie A leaders Juventus.
The match looked destined to be a goalless draw until Spanish forward Jose Callejon headed in a late winner.
Roma had carried the greater attacking threat in the first half, with Gervinho spurning two glorious chances.
But third-placed Napoli grew into the game after the break and Callejon's goal put them three points behind Roma.
Only the top two sides in Serie A automatically qualify for the following season's Champions League, with the third-placed team facing a two-legged qualifying tie to reach the group stage.
And it appears to be a two-way battle between Rafael Benitez's side and Roma for second place behind runaway leaders Juventus.
The visitors needed a win to keep their slim hopes of overhauling Juve alive and only Napoli keeper Pepe Reina's double save from ex-Arsenal forward Gervinho stopped the Giallorossi from going ahead before half-time.
The on-loan Liverpool keeper also blocked Roma right-back Maicon's deflected shot with a smart reaction save after the break.
But Rudi Garcia's men are now 14 points adrift of Juve after Callejon's far-post header, from Faouzi Ghoulam's left-wing cross, condemned them to only a second league defeat of the season.