Scotland will play their opening Euro 2016 qualifier with Germany in September at the home of Champions League runners-up Borussia Dortmund.
Gordon Strachan's team begin their bid to reach a first major finals in 18 years on 7 September at the 65,718-capacity Westfalenstadion.
For Dortmund's league matches, when standing is permitted, the stadium can hold up to 80,720 fans.
Scotland's last visit to Germany was a 2-1 defeat in Dortmund in 2003.
Fredi Bobic and Michael Ballack were on target in the Euro 2004 qualifier before Neil McCann pulled one back for Berti Vogts' side.
Scottish Football Association chief executive Stewart Regan confirmed the venue on Twitter, saying: "The German FA have now confirmed that Scotland will play Germany on 7th Sept in Dortmund. Get your flights sorted quickly! #comeonscotland."
Scotland will also take on Georgia, Poland, the Republic of Ireland and Gibraltar in Group D as they aim to reach the next European Championship finals in France.
When the draw was made last month, Strachan said: "The Germans might make one mistake, possibly two, but I don't think they have failed to qualify for a major tournament, so the rest of us will be looking for second place.
"It will be really tough for everyone in the group."
Full fixture list (all kick-offs in UK time)
Sunday 7 September: Germany v Scotland (19.45)
Saturday 11 October: Scotland v Georgia (17:00)
Tuesday 14 October: Poland v Scotland (19:45)
Friday 14 November: Scotland v Republic of Ireland (19.45)
Sunday 29 March 2015: Scotland v Gibraltar (17:00)
Saturday 13 June 2015: Republic of Ireland v Scotland (17:00)
Friday 4 September 2015: Georgia v Scotland (17:00)
Monday 7 September 2015: Scotland v Germany (19:45)
Thursday 8 October 2015: Scotland v Poland (19:45)
Sunday 11 October 2015: Gibraltar v Scotland (19:45)