Match ends, MK Dons 0, Wolverhampton Wanderers 1.
Wolves moved six points clear at the top of League One after substitute Liam McAlinden's first league goal for the club gave them victory at MK Dons.
Striker McAlinden headed in Kevin McDonald's cross a minute after Dons substitute Sanmi Odelusi was sent off for two bookings in two minutes.
Michael Jacobs and Nouha Dicko also went close for Wolves, while Dons' Dean Bowditch saw a free-kick tipped wide.
Defeat for the hosts left them three points off the play-off places.
It was the Dons' fourth successive home defeat but Wolves, who were backed by more than 8,800 fans as a new record attendance was set at Stadium MK, now have daylight between themselves and the chasing pack.
Wolves had marginally the better openings of a cagey first half as Jacobs shot tamely at home keeper David Martin, who also tipped over a Dicko effort.
Dicko went close again at the start of the second half, while at the other end striker Bowditch saw his free-kick pushed around the post by Wolves keeper Carl Ikeme.
But the game swung in the visitors' favour when Odelusi, a 58th-minute substitute, was shown two yellow cards in quick succession for fouls on Scott Golbourne.
And McAlinden, whose only previous senior Wolves goal came in a Johnstone's Paint Trophy tie against Walsall last August, made his side's numerical advantage count immediately when he nodded in to win it.
MK Dons boss Karl Robinson told BBC Three Counties Radio:
"I thought the players' hunger, their fight, determination and bravery, in and out of possession, was tremendous.
"These young players are getting tremendous experience; the future is certainly bright at MK Dons.
"You've got to accept we've been beaten here by the best team in the league. I think it was a very fair and equal game today.
"I think the players, young and old, gave everything they've got in their bodies and I don't think they could have done much more."
Wolves head coach Kenny Jackett told BBC WM:
"It was a terrific win here on a pitch that made it very difficult for both teams, we just had to find a way of winning.
"I just think you need a variation in tactics, you can't just play one way. Our midfield players have scored goals this season so it's worked for us.
"The advantage for myself is I've been around these leagues for a long time. I've just spent three years in the Championship and before that three years in League One.
"Look forward positively is the important thing for us now. We're hoping that Bakary Sako and perhaps Matt Doherty will come back."
- 24KayBooked at 29mins
- 29KennedySubstituted forOdelusiat 58'minutesBooked at 80mins
- 26LoveridgeSubstituted forRasuloat 73'minutes
- 9BowditchSubstituted forGallowayat 82'minutes
- 19PriceSubstituted forMcAlindenat 61'minutes
- 40DickoSubstituted forClarkeat 61'minutes
- Kevin Wright
- Shots on Target
Second Half ends, MK Dons 0, Wolverhampton Wanderers 1.
Foul by Jordan Spence (MK Dons).
Liam McAlinden (Wolverhampton Wanderers) wins a free kick in the defensive half.
Dean Lewington (MK Dons) wins a free kick on the right wing.
Foul by James Henry (Wolverhampton Wanderers).
Jordan Spence (MK Dons) wins a free kick on the left wing.
Foul by Leon Clarke (Wolverhampton Wanderers).
Foul by George Baldock (MK Dons).
Kevin McDonald (Wolverhampton Wanderers) wins a free kick on the right wing.
Bamidele Alli (MK Dons) wins a free kick in the defensive half.
Foul by Kevin McDonald (Wolverhampton Wanderers).
Substitution, MK Dons. Brendan Galloway replaces Dean Bowditch.
Goal! MK Dons 0, Wolverhampton Wanderers 1. Liam McAlinden (Wolverhampton Wanderers) right footed shot from very close range to the bottom left corner. Assisted by Kevin McDonald with a cross.
Second yellow card to Sanmi Odelusi (MK Dons).
Foul by Sanmi Odelusi (MK Dons).
Scott Golbourne (Wolverhampton Wanderers) wins a free kick in the defensive half.
Sanmi Odelusi (MK Dons) is shown the yellow card.
Foul by Sanmi Odelusi (MK Dons).
Scott Golbourne (Wolverhampton Wanderers) wins a free kick on the right wing.