Uruguay's game against England on Thursday represents "life or death" for both sides in this World Cup, according to captain Diego Lugano.
Central defender Lugano said: "Now we're united again. Our faith is intact. We mustn't lose our heads.
"We must keep having fun. It's not going to be easy. We have to improve."
Lugano is particularly aware of the threat England can pose having spent last season at West Bromwich Albion.
"The English players are fast and strong," said the 33-year-old. "That demands a lot of the defenders."
"We hope Luis plays, but, if not, it's up to the rest of us," said Lugano.
Coach Oscar Tabarez said England "deserved better luck against Italy".
He added: "It's a tough game but not impossible. We need a victory in order to progress and they do, too."
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