QPR centre-back Richard Dunne will be out for three months with a knee injury, but striker Charlie Austin expects to be back "in a week or two".
But the forward tweeted: "Delighted to say I've not broken a bone in my foot! Hopefully back in a week or two!"
Nedum Onuoha will be out for three to four weeks with a hamstring injury.
Defender Onuoha, 28, also sustained his injury during the defeat against Southampton.
Austin, QPR's leading scorer this season with 13 goals, completed the match at Loftus Road despite suffering heavy bruising to his right foot.
The 25-year-old will miss Tuesday's trip to Sunderland but is likely to be available to face Hull on 21 February.
Former Republic of Ireland captain Dunne, 35, injured his right knee and was replaced seven minutes from the end of Saturday's game, in which Sadio Mane's 93rd-minute goal left QPR in the bottom three, one point from safety.