Arjen Robben will miss the rest of Bayern Munich's season, including their Champions League semi-final against Barcelona, after tearing calf muscles.
The Dutch winger suffered the injury 16 minutes after making a return from a five-week absence as a substitute in Bayern's German Cup semi-final defeat by Borussia Dortmund on Tuesday.
Striker Robert Lewandowski was also injured, fracturing his nose and jaw.
But the Poland international hopes to make the first leg at Barca on 6 May.
"It's a few more days till the match at Camp Nou, I really hope I will be able to play," said Lewandowski, who was knocked to the ground by Dortmund goalkeeper Mitchell Langerak in extra time before a 2-0 penalty shootout defeat in which Bayern missed all of their spot-kicks.
The newly-crowned Bundesliga champions said more medical checks would be required to determine the length of Lewandowski's absence and that the 26-year-old had also been concussed.
Robben, 31, was returning from an abdominal injury suffered in March, a problem that meant he missed both legs of Bayern's 7-4 aggregate win over FC Porto in the Champions League quarter-finals.
Following the first leg in Portgual, Bayern doctor Hans-Wilhelm Muller-Wohlfahrt resigned after 38 years with the club, claiming the medical department had been blamed for the absence of key players' in the 3-1 defeat.