Match ends, Valencia CF 0, Lyon 2.
Gary Neville's first game as Valencia manager ended in defeat as the Spanish side lost 2-0 at home to Lyon to go out of the Champions League.
The hosts hit the post early on through defender Mustafi, who then had a goal disallowed for a push in the area.
Maxwell Cornet curled in a shot for Lyon before the break and Alexandre Lacazette calmly added their second.
"We must take defeat on the chin and realise it is unacceptable to lose at Mestalla," said Neville afterwards.
Joined in the dugout by his brother and assistant manager Phil, Neville was animated on the touchline and said the game could have been different had Mustafi's early goal been given.
"The players thought it was not a foul," added Neville, whose side drop into the Europa League. "I used to whinge a lot as a player, but won't blame referees as a manager unless I feel I have to. Tonight I don't as Lyon did well."
First game in management, but Neville 'didn't feel stressed at all'
A suit and a first taste of home anger

Valencia rallied for their new manager with 11 shots after half-time, but in the end the result was irrelevant as Gent's win over Zenit St Petersburg ensured the Spanish side would not have qualified even if they had won.
Neville, wearing a suit, stood in his technical area throughout much of his managerial bow but his side were jeered in parts by the home support, who have now seen Los Che win just once in six outings.
"We showed a lot of spirit and fight but didn't really create enough chances to win the game," added Neville, who succeeded Nuno Espirito Santo last week.
"I didn't feel stressed at all. I don't feel stress now. I'm disappointed."
Manchester United in Europe?

Three straight Champions League defeats, without scoring a goal, have ruined Valencia's European campaign and a number of injuries to first-team members did not help Neville in his first game.
They will return to La Liga action five points adrift of the qualification places for next year's competition but will be in this season's Europa League.
Valencia could meet Neville's old club Manchester United in that competition but, still smarting from the defeat, he said "at this moment I couldn't care whether we play Manchester United or someone else".

Roma's ugly route through
Bayer Leverkusen saw Barcelona goalkeeper Marc-Andre ter Stegen produce two stunning second-half saves in their 1-1 draw with the defending champions - a result which sees the German side eliminated.
Javier Hernandez struck his 12th goal in 11 club games to level Lionel Messi's early strike.
Roma, who drew 0-0 with BATE Borisov, finished second in the group on six points. Their tally equals the record low for any side reaching the knockout stages since the tournament moved to three points for a win.

Line-ups
Valencia
Formation 4-3-3
- 24Domenech Sánchez
- 2Cancelo
- 5MustafiBooked at 38mins
- 23AbdennourBooked at 24mins
- 14Gayá Peña
- 12Barbosa da SilvaSubstituted forNegredoat 52'minutes
- 10Parejo
- 15PérezSubstituted forFuego Martínezat 24'minutes
- 22Mina LorenzoBooked at 44mins
- 9Alcácer
- 20de PaulSubstituted forPiattiat 75'minutes
Substitutes
- 4Santos
- 7Negredo
- 11Piatti
- 18Fuego Martínez
- 25Ryan
- 28Carbonell Gil
- 33Gil de Pareja
Lyon
Formation 4-3-3
- 1Lopes
- 20da Silva
- 2Yanga-Mbiwa
- 15Morel
- 3Bedimo
- 14DarderSubstituted forKonéat 77'minutes
- 21Gonalons
- 8TolissoBooked at 68mins
- 27Cornet
- 10LacazetteSubstituted forBeauvueat 77'minutes
- 7GrenierSubstituted forGhezzalat 70'minutes
Substitutes
- 4Koné
- 5Bisevac
- 9Beauvue
- 11Ghezzal
- 17Malbranque
- 28Mvuemba
- 30Gorgelin
- Referee:
- Matej Jug
- Attendance:
- 32,494
Match Stats
- Possession
- Home56%
- Away44%
- Shots
- Home16
- Away13
- Shots on Target
- Home4
- Away6
- Corners
- Home14
- Away3
- Fouls
- Home16
- Away15
Live Text
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Full Time
Second Half ends, Valencia CF 0, Lyon 2.
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Corner, Valencia CF. Conceded by Rafael.
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Attempt blocked. Pablo Piatti (Valencia CF) right footed shot from outside the box is blocked. Assisted by Santi Mina with a headed pass.
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Foul by Santi Mina (Valencia CF).
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Rachid Ghezzal (Lyon) wins a free kick on the left wing.
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Foul by Shkodran Mustafi (Valencia CF).
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Rachid Ghezzal (Lyon) wins a free kick on the left wing.
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Offside, Valencia CF. João Cancelo tries a through ball, but Paco Alcácer is caught offside.
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Attempt missed. Javi Fuego (Valencia CF) right footed shot from the right side of the six yard box misses to the right. Assisted by João Cancelo with a cross following a corner.
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Corner, Valencia CF. Conceded by Henri Bedimo.
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Foul by João Cancelo (Valencia CF).
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Rachid Ghezzal (Lyon) wins a free kick on the left wing.
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Foul by Paco Alcácer (Valencia CF).
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Mapou Yanga-Mbiwa (Lyon) wins a free kick on the right wing.
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Attempt missed. Daniel Parejo (Valencia CF) right footed shot from outside the box is close, but misses to the left.
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Offside, Valencia CF. Daniel Parejo tries a through ball, but Paco Alcácer is caught offside.
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Foul by Santi Mina (Valencia CF).
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Henri Bedimo (Lyon) wins a free kick in the defensive half.
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Attempt missed. Aymen Abdennour (Valencia CF) header from the centre of the box is just a bit too high. Assisted by Pablo Piatti with a cross following a corner.