Derry City will begin their 2016 Premier Division campaign with a derby fixture against newly promoted neighbours Finn Harps at Finn Park.
The north west rivals will open their season on Friday 4 March.
Derry's first competitive home game under new manager Kenny Shiels will be against Cork City at the Brandywell on Friday 11 March.
The mid-season break will take place from Monday 6 June to Thursday 23 June, with the league ending in late October.
The Candystripes ended the 2015 league season in seventh position.