Football Association chief executive Martin Glenn has dismissed the idea of a European super league, arguing it would kill competition.
Leading Premier League clubs reportedly met this week to discuss the idea of a breakaway competition featuring the continent's top teams.
But Glenn said closing off the league to certain teams would put fans off.
"Football has to keep evolving [but] we can't lose the principles of promotion and relegation," he told the BBC.
Glenn, who was appointed a year ago, drew on the example of Premier League leaders Leicester, who would not be able to join the mooted elite should they go on to win the title.
He also said the way the Premier League distributed equal TV money to its clubs allowed teams such as the Foxes to attain their current status.
|Analysis from BBC 5 live sports news correspondent Richard Conway|
|The "secret" meeting of England's big five clubs has caused a backlash. Martin Glenn is the latest high-profile voice to join a chorus of disapproval over any suggestion of a breakaway league.|
|The fact remains that with an £8bn+ TV deal, Premier League clubs are the envy of Europe. There's no desire from the clubs to leave.|
|The future of European competition is what is at stake here. Uefa will take a new TV deal for 2018-21 to the market later this year and the clubs want a bigger slice of the cake.|
|Sabre rattling? Or a genuine threat to forge their own European series? History shows that Uefa and the clubs eventually settle their differences.|
Last season, Premier League teams earned £50m each, but in Spain, for example, Barcelona and Real Madrid earn a larger proportion of TV money than other clubs - although that is set to change this year.
From next season, when a new TV deal kicks in, the Premier League's bottom club will earn £99m, with the champions taking in excess of £150m in TV money.
Glenn added: "Isn't it brilliant to see a team like Leicester upsetting the applecart?
"And that's only possible because the Premier League shares the riches quite evenly, in contrast to most other European countries where a few teams get the lion's share.
"It would be a real shame to miss that, a real shame to not have a Leicester phenomenon every year to bring in some variety and challenge."
|Dan Roan analysis: Is football about to change forever?|