Reigning champions Etoile du Sahel took a step towards reaching the group stage of the Confederation Cup with a 2-0 win over Gabon's Mounana.
Tunisia Defender Zied Boughattas opened the scoring for the hosts on the stroke of half-time and Ihab Msakni added the second in the 65th minute.
The second leg of that tie is on 18 May in Gabon, with the overall winners progressing to group stage of the tournament.
Earlier on Friday it ended 0-0 between Al Ahly Tripoli and Misr Elmaqasah of Egypt, that games was played in Tunis because of the ongoing security concerns in Libya.
The tie will now be decided on 17 May in Egypt.
Etoile and Al Ahly Tripoli had begun the 2016 season in the African Champions League.