Match ends, Preston North End 2, Burton Albion 1.
Burton were relegated from the Championship after losing to 10-man Preston, who missed out on a play-off place despite the result.
Callum Robinson headed the hosts in front after Josh Harrop's corner was nodded across goal by Paul Huntington.
Burton were given hope when Preston forward Billy Bodin was given a second yellow card for simulation.
Hope Akpan fired in the equaliser from 25 yards out, but Louis Moult slotted in late on to win it for Preston.
But Alex Neil's side finished outside the top six, as Derby's 4-1 win over Barnsley assured the Rams of the final play-off spot.
- Relive all the action from the final day of the Championship season
- Championship stay has been 'fantastic' for Burton
Burton unable to repeat their heroics
The result meant the Brewers were unable to repeat their heroics of 2016-17, when they avoided relegation by a single point in what was their first season of second-tier football.
Nigel Clough's side appeared doomed this term after a 5-0 home loss to Hull on 10 April left them bottom of the table, seven points from safety with just four matches remaining.
But consecutive victories against Derby County, Sunderland and Bolton followed to give Burton real hope of another escape.
However, Sunday's defeat confirmed they would suffer relegation for the first time in 41 years.
For former Derby and Sheffield United boss Clough, it is the first time he has suffered relegation in his 20-year managerial career, 14 seasons of which have been spent with the Brewers.
Brewers' Football League journey
- 2008-09: Conference Premier champions.
- 2012-13: League Two play-off semi-finalists, losing to Bradford City over two legs.
- 2013-14: Beaten by Fleetwood in League Two play-off final.
- 2014-15: League Two champions and promoted to third tier of English football for the first time in their history.
- 2015-16: Second in League One in their first season of third-tier football, promoted to Championship for first time.
Preston manager Alex Neil:
"I've really enjoyed my year and there's much more to come going forward. We are not far away and we have improvement to make.
"We can reflect on the season and reflect on a few things that mean we have come up short, but also with a lot of pride in what we have managed to achieve.
"There are elements we need to improve. What we need is to push it on again and, if we can, improve the squad over the summer.
"I want to get as much as we can get done as early as we can and bring more competition into certain places. Without competition, improvement doesn't take place."
Burton Albion boss Nigel Clough:
"Everybody in the dressing room is really flat as you would expect. There are a lot of upset players in there.
"But we are down and have been relegated because of a reason - over 46 games we haven't been good enough it's as simple as that.
"We just didn't get enough points ultimately, we had too many draws and we wasted too many opportunities across the course of the season.
"What made it worse for us is that it all happened so late. Bolton were always going to be the problem. You always worry when your rivals are playing against a team with nothing to play for."
- 23HuntingtonBooked at 82mins
- 8BrowneSubstituted forMoultat 81'minutes
- 39BodinBooked at 50mins
- 10HarropSubstituted forGallagherat 69'minutes
- 24MaguireSubstituted forBarkhuizenat 59'minutes
- 15NaylorBooked at 42mins
- 12FlanaganSubstituted forDyerat 74'minutes
- 19DavenportSubstituted forBentat 61'minutes
- 10AkinsBooked at 80mins
- 27BoyceBooked at 48mins
- Andy Madley
- Shots on Target
Second Half ends, Preston North End 2, Burton Albion 1.
Foul by Louis Moult (Preston North End).
John Brayford (Burton Albion) wins a free kick in the defensive half.
Declan Rudd (Preston North End) wins a free kick in the defensive half.
Foul by Lucas Akins (Burton Albion).
Attempt missed. Liam Boyce (Burton Albion) right footed shot from the left side of the six yard box misses to the right following a set piece situation.
Attempt saved. Darren Bent (Burton Albion) right footed shot from a difficult angle on the right is saved in the top right corner. Assisted by Kyle McFadzean with a headed pass.
Offside, Preston North End. Ben Pearson tries a through ball, but Callum Robinson is caught offside.
Attempt blocked. Liam Boyce (Burton Albion) right footed shot from outside the box is blocked. Assisted by Marvin Sordell.
Attempt missed. Louis Moult (Preston North End) right footed shot from more than 40 yards on the right wing misses to the left.
Goal! Preston North End 2, Burton Albion 1. Louis Moult (Preston North End) left footed shot from the centre of the box to the centre of the goal. Assisted by Ben Pearson following a fast break.
Attempt blocked. Liam Boyce (Burton Albion) left footed shot from outside the box is blocked. Assisted by Marvin Sordell.
Attempt saved. Callum Robinson (Preston North End) left footed shot from outside the box is saved in the centre of the goal. Assisted by Ben Pearson.
Attempt missed. Callum Robinson (Preston North End) left footed shot from the left side of the box is close, but misses to the left. Assisted by Tom Barkhuizen.
Attempt missed. Paul Gallagher (Preston North End) right footed shot from outside the box is close, but misses to the left from a direct free kick.
Louis Moult (Preston North End) wins a free kick in the attacking half.
Foul by Hope Akpan (Burton Albion).
Attempt missed. Hope Akpan (Burton Albion) right footed shot from outside the box is too high from a direct free kick.
Foul by Darnell Fisher (Preston North End).