Bruno Senna will drive for Renault in the first practice session for the Hungarian Grand Prix on Friday.
The 27-year-old, who joined the team as their third driver in February, will take the wheel of Nick Heidfeld's car.
Heidfeld will return to the car to drive from second pratice onwards, alongside Vitaly Petrov.
"It's not very often you get these opportunities with big teams. Hopefully I can do a good job and show the team the potential I have," said Senna.
"I'm really excited to be driving in FP1 at the Hungaroring. I'm very grateful for getting this chance. I know the car layout well and I'm confident it will be a smooth transition. I'm looking forward to working with the team during the session to ensure a good car set-up for Nick when he resumes driving."
Heidfeld suffered a difficult weekend at the German Grand Prix, culminating in an early retirement from the race after he was involved in a crash caused by Toro Rosso's Sebastien Buemi, who was subsequently given a five-place grid penalty for Hungary.
Although he hinted he feels further disappointment at having to make way for Senna, the German said he backed his team.
"Firstly, I would like to say I'm fully behind the decision. Even though I would like to drive every session, it's important for Third Drivers to have a chance to practice throughout the year; it is a good opportunity for Bruno to get some valuable race weekend practice time," he said.
"I'm supportive of the team's decision and look forward to returning to the car from second practice onwards."