Tyrone defender Peter Harte has been ruled out of next weekend's All-Ireland qualifier with Armagh or Monaghan after breaking a wrist in a club game.
Harte suffered the injury while playing for Errigal Ciaran in a club game against Augher on Friday evening.
The wing back's absence is a major blow to the Red Hands' hopes of progressing in the All-Ireland Championship.
The setback comes just as Tyrone had returned to full strength after Joe McMahon's recovery from injury.
Harte could be ruled of action out for a number of weeks.
Mickey Harte's side will learn their opponents on Sunday, when Armagh play Monaghan in their Ulster Football Championship semi-final replay at Clones.