All-Star Mattie Donnelly has been left on the Tyrone bench for Sunday's Football League Division One game against Cavan despite being cleared to play following a concussion protocol.
Donnelly missed the draw with Dublin due to a bang on the head sustained in the opening day win over Roscommon.
Mickey O'Neill replaces Niall Morgan in goal as part of manager Mickey Harte's rotational policy.
Mark Bradley is suspended so Ronan O'Neill comes in at corner forward.
Bradley received a straight red card against the Dubs at Croke Park a fortnight ago.
Sean Cavanagh is still waiting for his first start of the season, having come in as a substitute against both Roscommon and Dublin.
Cavan and Tyrone both drew their last games, but it was the Breffni men who came out on top when the sides met in the opening Dr McKenna Cup game back in January.
Former Tyrone attacker Mattie McGleenan makes his first visit to Healy Park as Cavan manager, looking for his first win in the current campaign.
Monaghan manager Malachy O'Rourke has named the same team which started in the draw against Cavan for their game against Kerry in Killarney on Sunday.
O'Rourke will not be able to call up Doohamlet youngster Barry McGinn for the rest of the season after he suffered a cruciate ligament injury in a game against Derry last weekend.
Barton makes two Derry changes
Derry manager Damian Barton has made two changes from the hammering by Meath for Sunday's crucial Division Two game against table toppers Kildare at Celtic Park.
Keeper Ben McKinless, who was black carded in Navan, is replaced by Conor McLarnon while Oisin Duffin is drafted into the defence.
Struggling Down have drafted in Kevin McKernan and Ryan Johnston for their game against Meath on Saturday night, with the Mourne County badly needing a win after two comprehensive opening defeats by Fermanagh and Clare.
Down go into the game on a shocking run of 14 straight defeats in league and championship.
Fermanagh boss Pete McGrath has make five changes from the home defeat by Galway for their Division Two trip to Cork.
Keeper Thomas Treacy replaces Chris Snow with Mickey Jones, Ryan Hyde, Ryon Lyons and Eoin McManus taking over from Cian McManus, Paddy Reihill, Cathal Beacom and Paul McCusker.
Cork drew their opening against Galway but were beaten 1-14 to 1-8 by Kildare last time out.
Armagh and Antrim both in need of points
In Division Three, Armagh are also in need of points after the draw against Sligo and home defeat by Laois and manager Kieran McGeeney has drafted in experienced defender Brendan Donaghy and midfielder Ben Crealey for Sunday's game in Longford.
Aidan Forker and Ethan Rafferty drop out of the Armagh starting line-up.
Also in Division Three, struggling Antrim face a difficult home game against a Sligo side that defeated last year's All-Ireland semi-finalists Tipperary last time out.
After their opening draw against Armagh, Sligo look to be genuine promotion candidates while in contrast, the Saffrons are bottom of the table after a creditable opening defeat by Tipp was followed by an embarrassing 13-point hammering by Offaly.
Tyrone (v Cavan): M O'Neill; P Hampsey, R McNamee, C McCarron; T McCann, J McMahon, A McCrory; C Cavanagh, D McClure; C Meyler, N Sludden, P Harte; D McCurry, C McShane, R O'Neill.
Monaghan (v Kerry): R Beggan; F Kelly, D Wylie, R Wylie; K Duffy, N McAdam, C Walshe; D Hughes, K Hughes; K O'Connell, S Carey, G Doogan; C McCarthy, T Kerr, C McManus.
Kerry: B Kealy; S Enright, M Griffin, K Young; T Morley, P Crowley, R Shanahan; D Moran, J Barry; J Lyne, P Murphy, D Walsh; J Savage, P Geaney, J O'Donoghue
Derry (v Kildare): C McLarnon; N Keenan, C Nevin, P Hagan; N Forester, O Duffin, M McEvoy; J Kielt, C McAtamney; E Lynn, E McGuckin, C McWilliams; D Tallon, N Loughlin, B Heron.
Kildare: M Donnellan; M O'Grady, D Hyland, O Lyons; J Byrne, E Doyle, K Cribbin; K Feely, T Moolick; F Conway, N Kelly, P Cribbin; N Flynn, D Flynn, B McCormack.
Down (v Meath): M Reid; R McAleenan, G McGovern, D O'Hagan; D O'Hanlon, C McGovern, C Mooney; A Carr, P Turley; K McKernan, C Maginn, J Murphy; S Millar, B O'Hagan, R Johnston.
Meath: P O'Rourke; D Keogan, C McGill, R O Coileain; W Carry, B Power, S McEntee; B Menton, J Toher; A Forde, C O'Sullivan, C O'Brien; G Reilly, B Sheridan, D Lenihan.
Fermanagh (v Cork): T Treacy; M Jones, C Cullen, B Mulrone; D McCusker, R McCluskey, L Cullen; E Donnelly, R Hyde; A Breen, E McManus, R Lyons; E Courtney, Sean Quigley, T Corrigan.
Cork: R Price; J McLoughlin, T Clancy, K Crowley; T Clancy, J Loughrey, S Cronin; A Walsh, R Deane; B O'Driscoll, L Connolly, J O'Rourke; N Coakley, P Kelleher, P Kerrigan.
Armagh (v Longford): M McNeice; M Shields, C Vernon, P Hughes; B Donaghy, N Rowland, A McKay; S Sheridan, B Crealey; R Grugan, O O'Neill, N Grimley; A Duffy, S Campbell, O Mac Iomhair.
ALLIANZ FOOTBALL LEAGUE FIXTURES
SATURDAY - 19:00 GMT
Mayo v Roscommon, Castlebar
Down v Meath, Pairc Esler
Laois v Tipperary, Portlaoise
Carlow v Limerick, Dr Cullen Park
SUNDAY - 14:00 GMT unless stated
Donegal v Dublin, Ballybofey
Kerry v Monaghan, Killarney
Tyrone v Cavan, Healy Park, 14:30
Cork v Fermanagh, Pairc Ui Rinn, 13:00
Derry v Kildare, Celtic Park
Galway v Clare, Salthill
Antrim v Sligo, Corrigan Park
Longford v Armagh, Pearse Park
Offaly v Louth, Tullamore
Wicklow v London, Aughrim, 13:00
Wexford v Waterford, Wexford Park, 13:00
Westmeath v Leitrim, Mullingar