Dubai Prince will miss the 2,000 Guineas and Epsom Derby following a training setback.
He has been diagnosed with a hairline fracture of his right ilial wing and will need a few weeks to recuperate.
Godolphin racing manager Simon Crisford said: "It is a big shame as he had been shaping up nicely. He should be fine for later in the season."
Dubai Prince was about a 10-1 chance for the Guineas and 14-1 for the Derby, behind hot favourite Frankel.
He was unbeaten in two starts as a juvenile for Dermot Weld and is now trained by Mahmood Al Zarooni.
Godolphin still have Casamento and Saamidd engaged in the 2,000 Guineas and a decision regarding their participation will be made in the middle of next week.