Former Cheltenham Gold Cup winners Lord Windermere and Bobs Worth have been named among 35 initial entries for this year's race on 13 March.
Two-time King George VI Chase winner Silviniaco Conti is also included and will look to make it third-time lucky for the race.
The Paul Nicholls-trained nine-year-old fell and finished fourth in the last two renewals of the race.
The first five finishers in last year's contest could all face each other.
Lord Windermere, ridden by Davy Russell, trained by Jim Culloty and owned by Dr Ronan Lambe, held off the challenge of On His Own, The Giant Bolster, Silviniaco Conti and Bobs Worth to win in 2014.
Bobs Worth won the Gold Cup in 2013 for trainer Nicky Henderson.
Betfred Cheltenham Gold Cup, Friday 13 March 2015
(Horse, age, owner, trainer)
AL FEROF (FR)10John HalesPaul Nicholls
BALLYCASEY (IRE)8Susannah RicciWillie Mullins IRE
BLACK THUNDER (FR)8Donlon, MacDonald, Fulton & WebbPaul Nicholls
BOBS WORTH (IRE)10The Not Afraid PartnershipNicky Henderson
BOSTON BOB (IRE)10Andrea & Graham WylieWillie Mullins IRE
CARLINGFORD LOUGH (IRE)9J P McManusJohn Kiely IRE
CHAMPAGNE FEVER (IRE)8Susannah RicciWillie Mullins IRE
CONEYGREE8The Max PartnershipMark Bradstock
DJAKADAM (FR)6Susannah RicciWillie Mullins IRE
DON COSSACK (GER)8Gigginstown House StudGordon Elliott IRE
DOUBLE ROSS (IRE)9Options O SyndicateNigel Twiston-Davies
DYNASTE (FR)9John WhiteDavid Pipe
FINGAL BAY (IRE)9Carol SkanPhilip Hobbs
FIRST LIEUTENANT (IRE)10Gigginstown House StudMouse Morris IRE
HARRY TOPPER8A N SolomonsKim Bailey
HOLYWELL (IRE)8Gay SmithJonjo O'Neill
HOME FARM (IRE)8Chris JonesHenry de Bromhead IRE
HOUBLON DES OBEAUX (FR)8Mrs Julian BlackwellVenetia Williams
KINGS PALACE (IRE)7Drew, George & Johnson FamilyDavid Pipe
LORD WINDERMERE (IRE)9Dr Ronan LambeJim Culloty IRE
MA FILLEULE (FR)7Simon MunirNicky Henderson
MANY CLOUDS (IRE)8Trevor Hemmings Oliver Sherwood
MORNING ASSEMBLY (IRE)8Clipper Logistics Group Ltd Pat Fahy IRE
ON HIS OWN (IRE)11Andrea & Graham WylieWillie Mullins IRE
RIVER CHOICE (FR)12Fergus WilsonRichard Chotard FR
ROAD TO RICHES (IRE)8Gigginstown House StudNoel Meade IRE
SAM WINNER (FR)8Angela YeomanPaul Nicholls
SHUTTHEFRONTDOOR (IRE)8J P McManusJonjo O'Neill
SILVINIACO CONTI (FR)9Chris Giles & Potensis Bloodstock LtdPaul Nicholls
SMAD PLACE (FR)8Mrs Peter AndrewsAlan King
SPRING HEELED (IRE)8Dr Ronan LambeJim Culloty IRE
TAQUIN DU SEUIL (FR)8Martin Broughton & Friends 1Jonjo O'Neill
THEATRE GUIDE (IRE)8Jean BishopColin Tizzard
THE GIANT BOLSTER10Simon Hunt & Gary LambtonDavid Bridgwater
UNIONISTE (FR)7John HalesPaul Nicholls