Rachael Blackmore created history by becoming the first female jockey to win the Grand National, triumphing on Minella Times.
The 11-1 chance, trained by Henry de Bromhead, finished six-and-a-half lengths clear of stablemate Balko Des Flos (100-1), ridden by Aidan Coleman.
Irish horses filled the first five places with Any Second Now (15-2) third ahead of Burrows Saint (9-1) and Farclas (16-1).
Only 15 of the 40 runners completed the race.
The Long Mile, trained by Philip Dempsey and ridden by his son Luke, had to be put to sleep after suffering an injury while running on the flat between obstacles.
It is the second equine fatality from a total of 316 runners in eight editions of the race since safety changes.
This is the full result.
Place, horse, jockey, odds
1 Minella Times (Rachael Blackmore) 11-1
2 Balko de Flos (Aidan Coleman) 100-1
3 Any Second Now (Mark Walsh) 15-2
4 Burrows Saint (Patrick Mullins) 9-1
5 Farclas (Jack Kennedy) 16-1
6 Blaklion (Harry Skelton) 50-1
7 Discorama (Bryan Cooper) 16-1
8 Jett (Sam Waley-Cohen) 80-1
9 Cabaret Queen (Sean O'Keeffe) 80-1
10 Shattered Love (Kevin Sexton) 33-1
11 Alpha Des Obeaux (Jody McGarvey) 80-1
12 Hogan's Height (Gavin Sheehan) 100-1
13 Acapella Bourgeois (Danny Mullins) 20-1
14 Sub Lieutenant (Tabitha Worsley) 50-1
15 Class Conti (Brian Hayes) 66-1
Definitly Red - pulled up
Tout Est Permis - pulled up
Kimberlite Candy - pulled up
Milan Native - pulled up
Give Me A Copper - pulled up
Cloth Cap - pulled up
Chris's Dream - unseated rider
Talkischeap - pulled up
The Long Mile - pulled up
Bristol du Mai - pulled up
Potters Corner - pulled up
Lord du Mesnil - pulled up
Ok Corral - pulled up
Yala Enki - unseated rider
Ballyoptic - pulled up
Vieux Lion Rouge - fell
Mister Malarky - pulled up
Takingrisks - pulled up
Canelo - fell
Ami Desbois - fell
Anibale Fly - pulled up
Double Shuffle - fell
Minellacelebration - unseated rider
Magic of Light - Unseated rider
Lake View Lad - fell