Jose Mourinho says that he knew his side need to win all of their home games in the Europa League and he is happy with 'two clear penalties.'
- Pogba scores penalty after Mata fouled
- Martial adds second penalty after being fouled
- Pogba & Lingard score from long range
- Van Persie pokes in on return to Old Trafford
- Result: Inter Milan 1-0 Southampton
- Candreva scores winner against run of play
David de Gea now has to make a good stop to prevent a second Fenerbahce goal as Souza's low shot from range is pushed around the post.
Matt Plews: Nothing beats Giggsy's celebration against Arsenal in 1999 FA cup
Luka Foley: Tim Cahill's boxing vs the corner flag celebration tops the list for me.
Anife Faria: Cantona standing there, collar up, soaking up the total adulation of the faithful!! Couldn't beat it!!!
Harrison Short: Jimmy Bullard's celebration against City surely has to be one of the best of all time! Genius!
James Wall: Best celebration - Suarez vs Moyes
Crazy stuff in the Fenebahce back line. Anthony Martial is in on goal this time and he's bundled over by Sener Ozbayrakli. Great ball from Juan Mata.
Manchester United seeing all of the ball, with Michael Carrick ticking the play along nicely in midfield. The cameras pick out Henrikh Mkhitaryan in the stands. What's going on with him? A mystery man.
A few interesting faces in the Manchester United directors' box this evening.
A non-playing player - Henrikh Mkhitaryan.
An international manager - Roberto Martinez
A former international manager - Sam Allardyce.
The former England manager is sat a few seats along from one of the men who appointed him; former United chief executive and current FA vice-chairman David Gill.
Mark, Berkshire: Saints problem all season has been their inability to hit a barn door with a banjo in front of goal, paid for that continued failure tonight.
Shakhtar Donetsk have piled into a 4-0 lead over Gent with Brazilian international Bernard among the scorers in that Group H clash.
Ajax and Celta Vigo are playing out a corker. The Dutch visitors went 2-1 up away through a goal from Amin Younes, but Fabian Orellana has just put Celta back level in the 82nd minute.
And Azerbaijani champions Qarabag lead POAK Salonika through a strike from Spanish winger Dani Quintana in Group J.
Stunning save! Charlie Austin, eight yards out, hammered at goal, brilliantly saved by Samir Handanovic.
Not sure how he kept that out...
Internazionale are down to 10 men and Marcelo Brozovic can have nil complaints.
He was booked for a nasty tackle on Charlie Austin earlier and this is even worse, sliding through the heels of Pierre Hojbjerg. Two yellows = red and a chance for Southampton now...
BBC Sport at Old Trafford
Jose Mourinho did not say Henrikh Mkhitaryan was unavailable for selection when asked yesterday, so it can only be presumed he is.
Therefore, his absence, not just from the team but the Manchester United bench, is an odd one.
The Armenian has been injured, but he has not been part of a matchday squad since being substituted at half-time on his only start, against Manchester City last month.
Mourinho paid Borussia Dortmund £26.3m for him in July.
Scott Clark: Forget that lot ;) Not picking Papa Waigo, Chris Marsden and Marian Pahars in any ex-Saints XI is madness
Ooooh a shocker from right-back Cuco Martina! He just doesn't look up and plays a backpass which sells Fraser Forster horribly short, Inter captain Mauro Icardi is on it in a flash, Forster makes himself big(ger), Icardi tries to round him and Forster cuts out his backheel.
Great goalkeeping. Horrific defending.
Robin van Persie scored 35 goals in his first season for Manchester United, delivering the title in Sir Alex Ferguson's final year in charge.
He was a superb signing, but was gradually phased out before leaving for Fenerbahce last summer.
Now 33, can RvP come back to hurt United tonight?
Inter Milan striker Mauro Icardi may have upset some of the club's fans but manager Frank de Boer picks him to start. Former Cardiff midfielder Gary Medel is also in the Serie A side's line-up, while Ever Banega and Ivan Perisic are on the bench.
Inter Milan XI: Handanovic, Icardi, Medel, Santon, Eder, Murillo, Miranda, Gnoukouri, Nagatomo, Brozovic, Candreva.
Southampton make six changes from the win over Burnley on Sunday. Midfielder/full-back Sam McQueen, who came on as a substitute in that game, makes his first start for the club. Defender Maya Yoshida, midfielders James Ward-Prowse and Pierre Hojbjerg as well as forwards Shane Long and Jay Rodriguez also come into the side. The benched Jose Fonte, Jordy Clasie, Steven Davis, Charlie Austin, injured Matt Targett and rested Nathan Redmond are the ones to make way.
Club record signing Sofiane Boufal has yet to play for Southampton but is also a substitute.
Southampton XI: Forster, Yoshida, Long, Rodriguez, Tadic, Romeu, Martina, Ward-Prowse, Van Dijk, Hojbjerg, McQueen.