Fraser Forster is up, but Manchester United clear the corner.
Post update
Jose Mourinho sent to the stands. Handshakes with all the Southampton staff before disappearing.
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Post update
Southampton 0-1 Manchester United
Southampton corner. United fans are panicking.
SUBSTITUTION
Southampton 0-1 Manchester United
Another defender on for Manchester United. Daley Blind on, Marcus Rashford off. Can Southampton snatch a dramatic equaliser?
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Southampton 0-1 Manchester United
Phil Jones is OK to carry on and into stoppage time we go.
Post update
Southampton 0-1 Manchester United
Phil Jones is down and needs treatment after being headed... by team-mate Chris Smalling.
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Southampton 0-1 Manchester United
Ander Herrera, a second-half substitute, is booked. It is a needless one for kicking the ball away.
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Southampton 0-1 Manchester United
Five minutes plus injury time for United to hang on.
'Southampton best team by long distance'
Southampton 0-1 Manchester United
Pat Nevin
Ex-Chelsea winger on 5 live Sport
United have defended just about enough but Southampton have now had about seven chances. United are just not in the game.
Marcus Rashford, who started off so well - we have barely said his name in this half.
These are the chances Southampton have to take. They deserve to. They have been the best team in this half by a long distance.
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SUBSTITUTION
Southampton 0-1 Manchester United
Charlie Austin and James Ward-Prowse come on as Southampton go for broke. That's all of their substitutions done now.
YELLOW CARD
Southampton 0-1 Manchester United
Romelu Lukaku in the book after a challenge from behind on Mario Lemina. Seems a harsh one as he got the ball.
Post update
Southampton 0-1 Manchester United
Jose Mourinho, hands in pockets, is pacing up and down the technical area. He looks a worried man. He has every reason to be at the moment. Ten minutes left for his side to hang on.
Post update
Southampton 0-1 Manchester United
Southampton are pushing men forward, so they will leave themselves vulnerable at the other end. Ander Herrera has a chance to seal the victory for United, but shoots over the top from 15 yards out.
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CLOSE!
Southampton 0-1 Manchester United
So close yet again to a Southampton equaliser. Oriol Romeu shoots low left-footed from a tight angle. David de Gea looks beaten, but luckily for him the ball goes inches wide.
SUBSTITUTION
Southampton 0-1 Manchester United
Another change for Southampton, striker Manolo Gabbiadini coming on. No messing about from Jose Mourinho to that, with Chris Smalling set to come on as an extra defender for the visitors. Henrikh Mkhitaryan is the man to make way.
Live Reporting
Michael Emons
All times stated are UK
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Southampton 0-1 Manchester United
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You can follow all the Premier League reaction here.
Southampton 0-1 Manchester United
Romelu Lukaku scores his sixth Premier League goal of the season to give Manchester United a hard-fought victory at Southampton.
The report is now live on our football pages.
FULL-TIME
Southampton 0-1 Manchester United
It is all over. United hang on.
Post update
Fraser Forster is up, but Manchester United clear the corner.
Post update
Jose Mourinho sent to the stands. Handshakes with all the Southampton staff before disappearing.
Post update
Southampton 0-1 Manchester United
Southampton corner. United fans are panicking.
SUBSTITUTION
Southampton 0-1 Manchester United
Another defender on for Manchester United. Daley Blind on, Marcus Rashford off. Can Southampton snatch a dramatic equaliser?
Post update
Southampton 0-1 Manchester United
Phil Jones is OK to carry on and into stoppage time we go.
Post update
Southampton 0-1 Manchester United
Phil Jones is down and needs treatment after being headed... by team-mate Chris Smalling.
Post update
Southampton 0-1 Manchester United
Ander Herrera, a second-half substitute, is booked. It is a needless one for kicking the ball away.
Post update
Southampton 0-1 Manchester United
Five minutes plus injury time for United to hang on.
'Southampton best team by long distance'
Southampton 0-1 Manchester United
Pat Nevin
Ex-Chelsea winger on 5 live Sport
United have defended just about enough but Southampton have now had about seven chances. United are just not in the game.
Marcus Rashford, who started off so well - we have barely said his name in this half.
These are the chances Southampton have to take. They deserve to. They have been the best team in this half by a long distance.
SUBSTITUTION
Southampton 0-1 Manchester United
Charlie Austin and James Ward-Prowse come on as Southampton go for broke. That's all of their substitutions done now.
YELLOW CARD
Southampton 0-1 Manchester United
Romelu Lukaku in the book after a challenge from behind on Mario Lemina. Seems a harsh one as he got the ball.
Post update
Southampton 0-1 Manchester United
Jose Mourinho, hands in pockets, is pacing up and down the technical area. He looks a worried man. He has every reason to be at the moment. Ten minutes left for his side to hang on.
Post update
Southampton 0-1 Manchester United
Southampton are pushing men forward, so they will leave themselves vulnerable at the other end. Ander Herrera has a chance to seal the victory for United, but shoots over the top from 15 yards out.
CLOSE!
Southampton 0-1 Manchester United
So close yet again to a Southampton equaliser. Oriol Romeu shoots low left-footed from a tight angle. David de Gea looks beaten, but luckily for him the ball goes inches wide.
SUBSTITUTION
Southampton 0-1 Manchester United
Another change for Southampton, striker Manolo Gabbiadini coming on. No messing about from Jose Mourinho to that, with Chris Smalling set to come on as an extra defender for the visitors. Henrikh Mkhitaryan is the man to make way.
Get Involved #bbcfootball
Southampton 0-1 Manchester United
Corin Wright: The win is all that matters, but watching United invite wave after wave of pressure is horrible as a fan.
Post update
Southampton 0-1 Manchester United
Southampton have been on top in this second half, which has been very enjoyable. United hanging on at the moment.