St Helens will win the League Leaders' Shield with victory over Hull FC.
James Bentley and Jack Welsby come into the side for James Roby and Louie McCarthy-Scarsbrook.
Hull FC, who are looking to end a club-record run of eight successive defeats, have Jake Connor (hamstring) available for the first time since July.
Albert Kelly, Marc Sneyd, Mark Minichiello, Chris Green, Mickey Paea, Josh Bowden, Josh Griffin, Joe Westerman and Jack Downs are all out.
St Helens (from):Lomax, Makinson, Percival, Fages, Amor, Taia, Wilkin, Douglas, Knowles, Thompson, Richardson, Grace, Lees, Ashworth, Barba, Bentley, Smith, Costello, Welsby.
Hull FC (from):Shaul, Faraimo, Tuimavave, Talanoa, Taylor, Houghton, Hadley, Connor, Abdull, Washbrook, Fash, Manu, Litten, Lane, Miloudi, Matongo, Scott, Harris, Bienek.