Two of Gloucester's South African imports in hooker Franco Marais and lock Gerbrandt Grobler will make their debuts in Friday's Bristol Bears derby.
Back-rower Jake Polledri is named in the starting line-up with try-scoring flanker Ruan Ackermann moving to eight.
Bristol Bears coach Pat Lam has made nine changes for the second derby since their top flight return.
Scrum-half Harry Randall is among the faces added to the squad up against his old club, as is prop John Afoa.
Loose-head Yann Thomas also starts in the front row against his old club, while new signing Zane Kirchener is named on the bench.
Back-row George Smith had his suspension rescinded after a successful appeal at an independent disciplinary hearing in midweek. The former Wallaby had been dismissed in the defeat by Saracens on Saturday.