We'll leave you with these video highlights from an eventful day here at Wimbledon.
- Stephane Robert (Fra) / Dudi Sela (Isr) bts Marcos Baghdatis (Cyp) / Mikhail Youzhny (Rus) 6-7 6-2 6-3
- Anna-Lena Groenefeld (Ger) / Kveta Peschke (Cze) bts Svetlana Kuznetsova (Rus) / Roberta Vinci (Ita) 5-7 6-2 6-1
- Alexander Zverev (Ger) bts Mikhail Youzhny (Rus) 6-4 3-6 6-0 4-6 6-2
- Andrea Hlavackova (Cze) / Lucie Hradecka (Cze) bts Chen Liang (Chn) / Yafan Wang (Chn) 7-6 3-6 9-7
So, day six was eventful. The rain came down as Djokovic's reign came to an end.
Usually, we'd need a day off to recover and rest our tired little drop shots.
But we don't want to do that! Come back tomorrow for a Wimbledon bonus day.
Nine-time Wimbledon singles champion on BBC TV
Djokovic didn't look healthy, he didn't look right. I don't know how much of it is nerves or if there's something going on we don't know about. Today was about nerves and serves. History just got to him and maybe there was something wrong with his body.
Former Wimbledon champion on BBC Radio 5 live
I don't think Novak was himself and Sam Querrey played well. He's a very good grasscourt player and uncomfortable to play against when he's serving that well. Novak wasn't returning well, he was off.
Watch as Milos Raonic hits a ridiculous backwards overhead lob against Jack Sock.
The sixth seed has just made it through to round four after beating Sock in a tie-break in the third set.
Day six of Wimbledon 2016 will live long in the memory for one big reason: Novak Djokovic proved he was human after all.
If you want to catch up on the best bits, Today at Wimbledon is the place to be. BBC Two now or click on this link.
It was a helluva battle on Centre Court and it's 2014 semi-finalist Milos Raonic who is the victor.
The Canadian sixth seed sails through a tie-break to beat plucky American Jack Sock in straight sets.
He will now play David Goffin in the last 16.
Andy Murray asked if Djokovic's defeat helps his title bid:
"If I reach the final this might have some bearing but it doesn't right now. The next round will be tough and the bookies don't always get it right. They've made mistakes across a number of things in recent weeks. I need to win my matches."
BBC Sport's Hanne Davis: "The Wimbledon punters might be disappointed their Pimms was diluted by summertime showers earlier and no doubt the players were sick of walking in and out the dressing room.
"But spare a thought for the ground staff who probably pulled the covers on and off the courts more times today than they did in total during the sweltering heat of 2015's tournament.
"Days like today are particularly hard. As they're called to haul covers on and off within 15 minutes they also have to contend with the crowd who, without any play to watch, seek shelter in the bars. One drunken fan pulled on the cover's tab as the ground staff tried to roll it out. Ever polite, the girl who wrestled it back labelled it 'not helpful at all'.
"Mostly teenagers and students, they take the insults and jibes from disappointed fans on their chins. To add insult to injury, it hurts to put antibacterial gel on hands that have blisters all over them.
"One girl had to be carried off after her leg got caught under a heavy cover during a particularly hasty roll out. Slips and falls are part and parcel of their thankless task."
No drama for third seed Agnieszka Radwanska on court three.
The 2012 Wimbledon finalist eased to victory in straight sets against Katerina Siniakova.
She will now play 18th seed Dominika CIbulkova, Eastbourne champion, in the next round.
MIlos Raonic clocks up his 26th ace on his way to holding serve to take the third set to another tie-break.
If the Canadian gets through this, he's into the last 16.
Seven-time Grand Slam doubles champion
Lopez's volleying has not been quite as accurate or as aggressive as he's needed it to be.
The crowd are enthralled in this epic battle on Centre Court.
Milos Raonic keeps trying to break, but Jack Sock just won't be broken.
The Canadian fifth seed performs a ridiculous backwards overhead lob to snatch a point away, but Sock recovers to hold. Again.
Talking of Nick Kyrgios...
Just after he won the first set, the Australian had to take a medical timeout for a nasal problem.
It looked like a nose bleed that was bothering him, so the trainer came on and did this to him.
Andy Murray on potential fourth-round opponent Nick Kyrgios, and the Australian's controversial character:
"You guys try to wind Kyrgios up all the time. It's not fair. He hasn't really done much in comparison to other players but he gets asked the questions all the time.
"I'm sure he will get better over time with dealing with the attention. He's made mistakes but he gets a rough ride."
Seven-time Grand Slam doubles champion
Unless this set finishes 6-1 to one player or another I can't see them starting another set.
At 11am this morning this was the match which stood out to be the match of the day but little did we know what was to happen elsewhere. But this match has lived up to its billing. We've had some sensational tennis in this set.
Watch this brilliant rally between Nick Kyrgios and Feliciano Lopez.
Kyrgios has just broken the Spaniard and taken the first set 6-3.
NIck Kyrgios - you know, that quiet, unassuming lad from Australia - has won the first set against Spain's Feliciano Lopez.
The winner of this one on Court One will face Andy Murray in the last 16.
Jack Sock, complete with bling bling gold chains around his neck, lets out a whoop and holler as he rescues another two break points against Milos Raonic.
The crowd get behind him when he nails a drop shot to hold. He goes 3-2 up.
The American still has a lot of work to do to recover, though.
As an aside, this match has had 79 unreturned serves. Whopper.
Andy Murray on Novak Djokovic's surprise defeat:
"When Sam Querrey is serving well he's very difficult to beat. The run Novak has had has been incredible but history suggests you can't win every match.
"There will be a match where you don't play your best and your opponent does. I imagine Sam served really well though.
"Rather than a surprise we should be celebrating what Djokovic's done because he's broken so many records and won 30 consecutive Grand Slam matches in a row which is incredible. It's probably been the best 12 months in tennis for years."
Paul Christie: Sock might lose this but he has possibly the best forehand I've seen on tour this year
Jonathan Lansana: Raonic is one of my favourite players of the moment, support him in this match with Sock.
Tennis commentator on BBC Two
It is admirable enthusiasm from Jack Sock, fighting hard, often playing his best tennis when his back is against the wall and that's all you can ask from a pro. Already in this third set he's faced four break points and saved them all.
Andy Murray is talking to the press after beating John Millman in straight sets.
Asked about the roof not being closed during a day of rain, he said:
"It's an outdoor tournament so they need to try to play without the roof. It's frustrating to be on and off but it wasn't too bad. It's been a lot worse for other players.
"Some of the tennis I played has been very good. Today I had a tough 15 minute period at the end of the second set but came through it well and toughed it out to take the set."
Ah, here we go. Fist pumps on Centre Court.
Milos Raonic is sniffing a break at 0-40 but Jack Sock rides out the rocky waters to hold.
Nicely done by the American. We remain with serve in the third set.
Third seed Agnieszka Radwanska was inches away from going out of Wimbledon in the second round against Ana Konjuh, before the Croatian teenager crumbled after an injury.
Radwanska looks back on song now. She's taken a 5-2 lead against Katerina Siniakova over on court three.
Seven-time Grand Slam doubles champion
These guys have been waiting around a long time. When I looked at the schedule I thought 16:00 BST was a possibility. Players get nervous, it's no wonder they come out to a slow start.
The screws are turning on Centre Court.
Jack Sock has his first break point of the match, but Milos Raonic is feeling particularly stingy tonight.
The Canadian serves two colossal aces to undo Sock's good work and takes a two set lead.
The argy-bargy over on court 9 is finally over.
The now non-retired Lleyton Hewitt and Jordan Thompson have beaten Nicolas Almagro and David Marreno in the doubles first round.
Eventually, they came through 6-7 (8-6) 6-4 19-17. Took them nearly four hours, mind.
Nine Wimbledon singles titles between these two legends.
We finally have a break on Centre Court and it's gone to Milos Raonic.
The Canadian sixth seed leads 5-3 in the second set against Jack Sock, having taken the first set in a quickfire tie-break.
World number 10 Madison Keys has gone through to the last 16 after a three-set victory against Alize Cornet.
It means wallflower Nick Kyrgios and Feliciano Lopez are out on Court One. Watch the match live on this link.
Three-time Wimbledon singles champion on BBC TV
Can we fast-forward this set to the tie-break?
We are still going with serve on Centre Court between Milos Raonic and Jack Sock, after Raonic took the first set in the tie break.
The Canadian has only dropped five points on his serve so far. Blimey.
BBC Sport at Wimbledon
Imagine putting in a few days' graft and then having your pay packet slashed by almost a third. Heather Watson only has herself to blame.
The British number two has been fined $12,000 (£9,043) for jamming her racket into the lush Wimbledon grass during her first-round defeat by Annika Beck.
That's the tennis equivalent of scraping your keys down the bonnet of your boss's flashy new motor.
It is the second biggest fine in SW19 history. Italian Fabio Fognini was handed a record $20,000 (£15,702) penalty for behaving rather badly in 2014.
It's still kicking off over on Court Nine - both on an off the grass.
Three-time Wimbledon singles champions on BBC TV
Djokovic's defeat is completely shocking, obviously. Sam Querrey is someone that in America we've been concerned about his intensity at times, and whether he has the competitive juices to wrestle with the top players.
With Serena last year so close to the Slam, and Novak this year, we see how difficult it is to maintain that intensity for so long.
She put in a stunning performance to beat British number one Johanna Konta in the second round but Eugenie Bouchard is now out of the ladies' singles.
She's gone down in straight sets against Eastbourne champion Dominika Cibulkova, who you may remember from earlier as the ball-sniffer.