Stephen O'Neill scored the only goal as Tyrone defeated Antrim 1-12 to 0-10 in Sunday's McKenna Cup Section A encounter at Casement Park.
The Saffrons led 0-5 to 0-3 but Tyrone hit six points without reply before susbtitute O'Neill netted.
Fermanagh cruised to a 2-14 to 0-10 win over Queen's University at Brewster Park with Seamus Quigley (1-9) and Paul Ward hitting second-half goals.
Tyrone and Fermanagh are locked on four points after two victories.
The Ernemen held a 0-9 to 0-5 advantage at the break before surging clear in the second half.
However, the hosts were reduced to 14 men when Paul Cosgrove was sent-off for two yellow cards midway through the half.
The introduction of Reds Hands forward O'Neill after 29 minutes proved to be the turning point in Belfast.
O'Neill and Peter Harte each fired over two points in Tyrone's superb start to the second half, with Stephen McNally and Cathal McCarron also on target.
O'Neill sealed the points three minutes from time when he rounded keeper Chris Keer before slotting in.
McKenna Cup results
Saturday 14 January
Derry 1-16 0-14 UUJ (Celtic Park)
Sunday 15 January
Antrim 0-10 1-12 Tyrone (Casement Park)
Fermanagh 2-14 0-10 Queen's (Brewster Park)
Monaghan 0-11 4-12 Down (Clones)
Armagh 1-18 0-10 St Mary's College (Athletic Grounds)
Cavan 1-14 2-8 Donegal (Breffni Park)