St Helens' Australian prop Josh Perry will miss the rest of the season after being told that he needs to undergo hamstring surgery.
The 30-year-old Australian has already suffered an injury-jinxed first year in English rugby league.
But this latest blow, sustained in the early stages of Saints' 28-14 win over Hull last Friday, will sideline him for up to three months.
"It's a season-ending injury," confirmed Saints coach Royce Simmons.
"He's done the tendon at the top of his hamstring and he's on his way to London to see a specialist."
Perry, who joined St Helens during the close season after two years with Manly Sea Eagles in the NRL, will have an operation later this week.
It is the latest blow in an injury-ravaged 12 months for Perry, who missed the opening month of the season while recuperating from a broken leg.
And, although one of the games he missed was due to a one-match ban for fighting with Crusaders second row Ben Flower in May, he has appeared in just 10 of his side's 21 Super League fixtures so far.
"He'll feel disappointed about his first season in England," said Simmons. "He's bounced from one injury to another."
The loss of Perry is offset by the return to fitness of Paul Clough, who had been out for four months with a shoulder injury but will make his comeback in Sunday's game at Wakefield.
Saints will also have front rower Louie McCarthy-Scarsbrook back from a one-match ban, while England centre Michael Shenton has now fully recovered from an ankle injury.