England have suffered a setback ahead of the Four Nations Series with the loss of Wigan captain Sean O'Loughlin.
The 28-year-old loose forward is to undergo surgery on a hip injury later this week, but will recover in time for the Warriors' pre-season preparations.
He has previously been forced to withdraw from the 2008 World Cup squad, as well as the 2009 Four Nations.
England coach Steve McNamara will announce his 24-man squad for the forthcoming tournament on Monday.
O'Loughlin missed just one of Wigan's 36 games this season and lead the Warriors to their first Challenge Cup win since 2002.
But his side missed out on the chance to land a historic double after they were beaten 26-18 in the Super League play-off semi-finals by St Helens.
England begin their campaign against Wales on 29 October at Leigh Sports Village, before taking on Australia at Wembley on 5 November and New Zealand at Hull's KC Stadium a week later on November 12.
O'Loughlin's injury is the second in the forward department for England, after Huddersfield prop Eorl Crabtree was ruled out of the tournament to undergo a shoulder operation.