Grand Final winners Leeds Rhinos will host Hull FC in the first fixture of the 18th Super League season, which begins on Friday, 1 February.
Challenge Cup holders Warrington take on Castleford in the opening round.
All 14 Super League clubs will head to Manchester City's Etihad Stadium for the Magic Weekend on 25-26 May 2013.
Bradford will play Huddersfield on the Saturday, with the Hull derby on Sunday followed by the Rhinos against 2012 League Leaders Wigan.
The 2013 season will also feature a return to Monday night Super League action, with nine matches scheduled to take place during the course of the campaign.
The regular season finishes on the weekend of 6-8 September. The top eight clubs will then progress to the play-offs, which culminate in the Grand Final at Manchester United's Old Trafford stadium on 5 October.
Super League clubs will enter the Challenge Cup in the fourth round, which takes place over the weekend of 20-21 April. The final is at Wembley on 24 August.
Three weeks after the Grand Final, the month-long 14-nation World Cup gets under way with England taking on Australia and Wales hosting Italy at Cardiff's Millennium Stadium. New Zealand are the defending champions. The final is at Old Trafford on 30 November.
A full list of fixtures can be found at the official Super League website.
Leeds v Hull FC - Fri, 1 February
St Helens v Huddersfield - Sat, 2 Feb
Salford v Wigan - Sat, 2 Feb
Bradford v Wakefield - Sun, 3 Feb
Hull KR v Catalan - Sun, 3 Feb
London v Widnes - Sun, 3 Feb
Warrington v Castleford - Sun, 3 Feb