Featherstone Lions and Castleford Lock Lane guarantee amateur representation in the Challenge Cup fifth round, where they could face a Super League club.
The pair will meet in round four, with 2015's top-flight bottom four joining at the next stage.
Fellow amateurs and National Conference League side Pilkington Recs host Championship side Halifax and Cumbrian outfit Kells are away to Oldham.
Fax's near neighbours Siddal go to League One Rochdale Hornets.
Ties will be played on 19-20 March.
Batley Bulldogs v Whitehaven
Hunslet Hawks v Doncaster
Sheffield Eagles v Swinton Lions
Featherstone Lions v Lock Lane
Oldham v Kells
Rochdale Hornets v Siddal
Pilkington Recs v Halifax
Dewsbury Rams v Bradford Bulls
Leigh Centurions v Workington Town
York City Knights v Keighley Cougars
London Broncos v Featherstone Rovers
Toulouse v University of Gloucestershire All Golds.