Ospreys flanker Ben Lewis has retired from the game after taking medical advice.
The 24-year-old openside suffered a neck injury in the 38-6 win over Aironi in September 2010.
But although he has returned to action for feeder club Swansea in February and showed no effects, the decision was made to stop playing.
"I've come to a decision which is the right one for me personally," said Lewis.
"Regrettably, this means that I have to give up rugby, but some things in life are more important than the game, life will still go on for me.
"I'm still young so there will be plenty of opportunities ahead for me.
"I'm not going to rush into making any decisions at the moment, I'll take my time and look at the options available before deciding what's next for me."
Capped by Wales at all the age-grade levels, Swansea-born Lewis came through the ranks at Mumbles and Swansea before he made his Ospreys debut against Leinster at Donnybrook in January 2007.
He made 24 Ospreys appearances in total, scoring three tries, but his time was hampered by injury.
Lewis had only just forced his way back into the regional side before suffering his neck injury after spending 16 months out following two knee injuries.
Ospreys physio Chris Towers said: Despite satisfying all the physical objectives, on his return to rugby in February, to play in the Premiership for Swansea, he suffered subsequent symptoms, happily with no residual issues.
"However, the nature of the symptoms are such that regrettably it is in his best interests to follow the medical advice he has received."