Wales' James Hook kicked a long-range drop goal and two conversions as he starred on his fly-half debut for Perpignan at Toulouse.
Hook also created the opening try after three minutes with a cross-kick for wing Farid Sid to score.
But the hosts came out on top 21-17 with ex-Sale playmaker Luke McAllister, the former New Zealand All Black, kicking 18 points.
McAllister's replacement, Lionel Beauxis, kicked the final penalty.
Hook's fellow Wales World Cup and Ospreys squad member Lee Byrne also made his debut in French rugby.
Byrne's side Clermont Auvergne went down to a 37-16 defeat at Stade Francais.