Northampton Saints forward Adam Eustace has been forced to retire because of a neck injury.
Eustace's only appearance this season came as a late replacement against Saracens in the LV= Cup in October.
The 32-year-old has featured just four times since arriving in the summer of 2010 from home town club Gloucester, for whom he played 242 times.
"It's been hard to take on the chin, and I'm pretty emotional about it, to be honest," said Eustace.
"For the first time in my career I've had one injury after another and it's been very frustrating to say the least.
"I'm indebted to the club for giving me all the time I've needed to get myself back, but unfortunately I've been given the advice from specialists to stop playing."
The second row forward made his debut Gloucester in 1998, leaving to join Scarlets in 2007, before returning to Kingsholm a year later.
Since arriving at Saints he has found first team opportunities hard to come by, but did make one of his four appearances against his former club Gloucester in April.
"While Adam has been a good person to have around the squad and contributed a great deal behind the scenes it is very unfortunate that he has not been able to show the fans his abilities as a player in the first team," said Saints boss Jim Mallinder.
"It is always sad to see a player have his career ended by injury, but we wish Adam all the best with his rehabilitation and every success with whatever he chooses to do in the future."