Leicester skipper Geordan Murphy says Ulster have been setting their sights on their Tigers clash and will be well rested for Friday's Heineken Cup tie.
Tigers need a win to keep alive their hopes of topping Pool Four and gaining home advantage in the quarter-finals.
But Murphy told BBC East Midlands Today Ulster's may give them the advantage.
"They're targeting Europe and have rested players. We have some injuries but have some quality players in the squad and they must step up," he said.
The Ireland full-back says the quality and relentless fixture schedule in England has meant their preparations have not been ideal.
"It's been a tough few weeks, but it always is," he added.
"The nature of our domestic competition is that we have to target every game and scrap for points in every game."
However, Murphy said the magnitude of the game should ensure Tigers rise to the challenge.
Ulster are top of the pool with 14 points and the Tigers trail them by two going into Friday night's crunch match.
Clermont Auvergne are just one point behind Leicester in the standings and travel to Aironi this weekend before hosting Ulster the following week.
"It [Ulster game] is massive," Murphy continued. "It's a winner-takes-all fixture. If we don't get a win this weekend then potentially it's us out of the European Cup, so it's as big as it comes.
"They have a very good home record. They are very successful at Ravenhill and it's a fortress for them."