Luke Narraway has been called up to England's training camp ahead of the Six Nations as cover for injured flanker Tom Wood.
Wood will miss the opening two games, against Scotland and Italy, because of a damaged big toe.
Gloucester number eight Narraway, 28, has seven caps, the most recent against Ireland at Croke Park two years ago.
With Wood absent, Calum Clark or Scarlets number eight Ben Morgan could earn a debut in a new-look back row.
Wood, who has been touted as a possible England captain, will wear a protective boot for four weeks, ruling him out of the away matches on 4 and 11 February.
The injury will further limit interim head coach Stuart Lancaster's options for his first match in charge with fellow elite squad members Toby Flood,Courtney Lawes, Louis Deacon and Manu Tuilagi also ruled out.
Meanwhile, Bath winger Matt Banahan and London Irish full-back Delon Armitage, who both played in last year's World Cup, are in the second-string 25-man England Saxons squad.
Harlequins centre Matt Hopper is one of five new players in the squad to face the Ireland Wolfhounds at Exeter on Saturday.
Leicester lock Ed Slater and Sale flanker Kearnan Myall are also included, in place of Henry Trinder of Gloucester, Leicester's Geoff Parling and Dave Attwood of Bath, who have all joined the senior squad for training.
London Irish scrum half Paul Hodgson and Gloucester prop Rupert Harden are in as temporary injury replacements for Karl Dickson of Harlequins and Sale's Henry Thomas.