Each week, former England and Lions centre Jeremy Guscott gives his predictions for the upcoming round of Premiership fixtures.
This week, leaders Harlequins take on struggling London Irish at Twickenham, while Gloucester travel to Northampton in the battle for a play-off spot.
All games are on Saturday unless stated.
Sale v Worcester
Prediction: Home win, Sale by three to six points.
Match report: Sale 33-27 Worcester
Harlequins v London Irish
Prediction: Harlequins to win by 12 points or more.
Exeter v Bath
Prediction: Exeter to win by six to nine points.
London Welsh v Wasps
Prediction: Welsh fans are going to hate this, but I'm going for a home win by three to six points.
Leicester Tigers v Gloucester
Prediction: Home win by six to nine points.
Saracens v Northampton
Prediction: Home win by nine or more points.