Schools' Cup holders Methodist College will face Royal School Armagh in the 2013 semi-finals after beating Wallace High 23-0 in the last eight.
Armagh were 25-0 winners away to Bangor Grammar in Saturday's quarter-finals.
Royal Belfast Academical Institution have been drawn against last year's runners-up Ballyclare High in the semi-finals to be played at Ravenhill.
Inst beat Limavady 41-10 while Ballyclare were 12-10 winners over Sullivan Upper of Holywood.
Rory Campbell, Toby Todd, Iain Jones, Fraser Wright, Andrew McGrath, Josh Atkinson and James Carruthers got the tries in Inst's win over Limavady whose only try was scored by Jack Elliott.
Danske Bank Ulster Schools' Cup semi-finals
RBAI v Ballyclare HS (Monday, 4 March)
RS Armagh v Methody (Wednesday, 6 March)