Gethin Jenkins will win his 100th cap for Wales only five months after "one of the lowest points" of his career.
The Cardiff Blues prop will join Stephen Jones, Gareth Thomas and Martyn Williams in winning a century of Wales caps at the Millennium Stadium on Saturday.
But Jenkins, 33, says missing the victorious 2013 British and Irish Lions tour of Australia still rankles.
"It was probably one of my lowest points," he said.
"Having to leave the Lions tour after working four years to get there, getting selected and then having to go home was tough."
Jenkins had to fly home because of a calf muscle injury and did not play a game.
Having toured with the Lions in 2005 and 2009, playing five Tests, he missed out on being part of 2-1 Test series victory against Australia in the summer.
Jenkins, who made his Wales debut 11 years ago against Romania at the Racecourse in Wrexham, has won four Six Nations titles, three Grand Slams and played in a World Cup semi-final.
"I suppose it's a weight off my mind, really," he said of winning his 100th cap.
"You are so tied up in the week with the build-up to the game. I suppose that afterwards I can look back and think, 'Yes, I got to 100'.
"I don't remember much about my first cap, although I do remember being pretty nervous before it.
"It was up in Wrexham, which was a bit different from the Millennium Stadium, but I can't remember anything that happened in the game."
Jenkins believes his longevity in the Test arena is down to his ability to adapt to the changing demands of rugby.
"You see some boys fall away when the game changes, but I am happy that I have managed to adapt," said Jenkins.
"I still like to do the stuff away from the scrum, but in the last three or four years there has been a lot more emphasis on the scrum and a lot more responsibility on you to work hard in that area.
"Previously, it was perhaps more of a looser game and defences weren't as good, but you just have to adapt. I pride myself on getting around the field, and there are no hiding places now, either.
"You have got a GPS on your back and a heart-rate device on your chest, so they (coaches) know everything you are doing."
Jenkins, who has set his sights on playing in the 2015 World Cup, says Wales' 2005 Grand Slam was the highlight of his career.
"Probably the Grand Slam game of 2005 against Ireland sticks out - just for the simple fact I scored a try," said Jenkins.
"That day was massive because it was the first time we had done it (Grand Slam) in 20-odd years, and to be a big part of it and score a try was a great memory."