Eastern Province Kings head coach, ex-New Zealand fly-half Carlos Spencer, has named his line-up to face Wales on 10 June.
The game kicks off the tour in which Wales twice face South Africa and is intended as a warm-up for the 32-strong tour party.
Warren Gatland's side go on to face the Springboks in two Tests.
They face the hosts in Durban on 14 June and in Nelspruit a week later.
EASTERN PROVINCE KINGS
Hansie Graaff; Siviwe Soyizwapi, Ronnie Cooke, Shane Gates, Scott van Breda; George Whitehead, Kevin Luiter; Lizo Gqoboka, Edgar Marutlulle, Charl du Plessis, Darron Nell, Cameron Lindsay, Thembelani Bholi, Paul Schoemnan, Devin Oosthuizen.
Replacements: Albѐ de Swardt, BG Uys, Simon Kerrod, Steven Cummins, Stefan Willemse, Jaco Grobler, Dwayne Jenner, Ntabeni Dukisa.