England fly-half Owen Farrell has been ruled out of the third Test against New Zealand with a knee injury.
Farrell, 22, has suffered a strain to the medial ligament in his left knee, which means he will miss Saturday's final game in Hamilton.
England head coach Stuart Lancaster said: "It's disappointing for Owen as he was desperate to play in the final Test."
New Zealand hold an unassailable 2-0 lead in the series.
Farrell will stay with the squad for the remainder of the tour before returning to his club Saracens for further assessment and treatment.
Lancaster added: "Such is his character that he is already working on his rehab and still contributing to the tour.
"Fortunately, we have three other fly-halves and we'll make that selection call over the next few days."
However, Lancaster said scrum-half Danny Care missed training earlier on Tuesday and is rated 50-50 "at best" for Saturday's Test, though centres Billy Twelvetrees and Luther Burrell will be available for selection.